I have a clean install on the latest and greatest: Windows Server 2008, SQL Server 2008 and MOSS 2007 SP1 with all updates. This is the layout of my farm:
http://<server>:80 - Portalhttp://<server>:8000 - Central Adminhttp://<server>:8001 - SSPhttp://mysite - MySitesEverything works fine, except the search crawl gave Access Denied errors on http://mysite and sps3://mysite.